Process for the preparation of n,n'-disubstituted...

C - Chemistry – Metallurgy – 07 – C

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260/466.05, 260/

C07C 15/24 (2006.01) A61K 31/155 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01)

Patent

CA 1130305

ABSTRACT N,N'-disubstituted 2-naphthaleneethanimidamide is prepared by the conversion of a nitrile into the novel imido ester salt intermediate by alcoholysis followed by treatment of the intermediate with an alklamine to give the product. The final products display central nervous system activity e.g. antidepressant.

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