Process for the preparation of new oxime derivatives of...

C - Chemistry – Metallurgy – 07 – D

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C07D 501/20 (2006.01) A61K 31/545 (2006.01) C07D 501/06 (2006.01) C07D 501/22 (2006.01) C07D 501/24 (2006.01) C07D 501/34 (2006.01) C07D 501/36 (2006.01) C07D 501/56 (2006.01)

Patent

CA 1315274

PRECIS DE LA DIVULGATION: L'invention concerne les nouvelles céphalosporines de formule I : Image isomère syn, dans laquelle R est un alkyle de 1 à 5 car- bones, un radical -CH2-S-R1 dans lequel R1 est un radical 2-méthyl 1,3,4-thiadiazolyle, 1-méthyl tétrazolyle ou 3-alkyl ou 3-alkoxy 1,2,4-thiadiazolyle ou R1 est un acyle de 2 à 4 carbones et A est un hydrogène, un équivalent d'alcalin, d'alcalino-terreux, de magnésium ou de base organique aminée, ainsi que leur procédé de préparation. Les composés I possèdent des propriétés antibiotiques.

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