Process for the preparation of nojirimycin and related...

Details Process for the preparation of nojirimycin and related... Process for the preparation of nojirimycin and related...

C - Chemistry, Metallurgy

07

D

260/228, 260/291

C07D 211/46 (2006.01) C07D 211/96 (2006.01) C07D 493/14 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2032310

ABSTRACT OF THE DISCLOSURE The present invention relates to an efficient new route for the preparation of (+)-nojirimycin and (+)-1-deoxy- nojirimycin which involves the steroselective reductive amination of 1,2-O-isopropylidene-5-oxo-.alpha.-D-glucurono- lactone. The reductive amination uses particular oximes of the 5-oxo compound. M01443A US

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