Process for the preparation of novel 2-thienyl-oxyacetic...

Details Process for the preparation of novel 2-thienyl-oxyacetic... Process for the preparation of novel 2-thienyl-oxyacetic...

C - Chemistry, Metallurgy

07

D

260/328.2

C07D 333/32 (2006.01)

Patent

CA 1320492

Abstact The invention relates to a process for the preparation of novel 2-thienyloxyacetic acid derlvatives of the formula I I Image in which R denotes a phenyl or thienyl group which is optionally mono- or polysubstituted by halogen, tri- fluoromethyl or C1 - C4 alkyl, and of pharmaceutically usable salts thereof by oxidation of the corresponding sulfonamide alcohol of formula II with Ag2O and if appropriate conversion of the free acid into a salt. These compounds can be used for the treatment of thromboses, inflammations, high blood pressure, apoplexy and angina pectoris.

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