Process for the preparation of novel...

Details Process for the preparation of novel... Process for the preparation of novel...

C - Chemistry, Metallurgy

07

D

260/276.1

C07D 495/04 (2006.01) C07D 211/78 (2006.01)

Patent

CA 1202974

PRECIS DE LA DIVULGATION: L'invention concerne la préparation de nouvelles benzothiopyranopyridinones, ainsi que de leurs sels, de formule (I): Image (I) où A, B, C et D, identiques ou différents, représentent hydrogène, alcoyle (1-6c), alcoxy (1-6c), NO2, NH2, acyl- amino (2-7c) ou halogène ou l'un de A et B ou C et D forment un cycle benzénique, R est hydrogène ou R', R' étant alcoyle (1-3c) ou alcényle (2-9c) éventuellement substitué par hydroxy, ou R' étant cycloalcoyle (3-9c), phényle, aralcoyle (7-9c) ou -(CH2)n-Z, n étant 1, 2, 3 ou 4 et Z cycloalcoyle ou cycloalcényle (3-9c), dioxanyl, 2-oxo benzimidazolyl, benzoyle, halobenzoyl, alcoxycarbonyl (2-7c), cyano ou car- bamoyl. Les produits (I) et leurs sels pharmaceutiquement acceptables peuvent être utilisés comme médicaments, notam- ment antidopaminergiques, antidépresseurs et antipsychoti- ques.

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