Process for the preparation of novel n-substituted...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/18 (2006.01) C07D 211/22 (2006.01) C07D 211/42 (2006.01) C07D 211/70 (2006.01) C07F 3/02 (2006.01)

Patent

CA 1087191

PRECIS DE LA DIVULGATION: Nouveaux dérivés N-substitués de la phényl-pipéridine répondant à la formule générale (I): Image (I) dans laquelle X représente un atome d'hydrogène ou un radical acyle renfermant de 2 à 6 atomes de carbone et R représente un radical alcoyle renfermant de 1 à 5 atomes de carbone, un radi- cal alcényle renfermant de 2 à 5 atomes de carbone ou un radical phényl alcoyle dont le radical alcoyle renferme de 1 à 3 atomes de carbone, ainsi que leurs sels d'addition avec les acides minéraux ou organiques pharmaceutiquement acceptables, et un procédé pour leur préparation. Ces dérivés possèdent des pro- priétés dopaminergiques et certains, des propriétés hypotensives.

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