Process for the preparation of novel piperidine derivatives

Details Process for the preparation of novel piperidine derivatives Process for the preparation of novel piperidine derivatives

C - Chemistry, Metallurgy

07

D

260/261, 260/266

C07D 215/22 (2006.01) C07D 211/58 (2006.01) C07D 401/14 (2006.01)

Patent

CA 1103250

Abstract of the Disclosure Piperidines of the formula Image (I) in which R1 is a substituted or unsubstituted heteroaryl radical, alk1 and alk2 independently of one another are lower alkylene radicals, each of which separates by 2 carbon atoms the nitrogen atom bonded thereto from the methine group bonded thereto, R2 is a free or acylated hydroxyl group, Ph is a substituted or unsubstituted o- phenylene radical, n is 0 or 1, R3 is a hydrogen atom, a lower alkyl radical or a hydroxyl group and R5 is a lower alkyl radical or a hydrogen atom, or R3 and R5 together are a second bond and R4 and R6 are each a hydrogen atom, or R4 together with R3 is an oxo group, R5 is a lower alkyl radical or a hydrogen atom and R6 is a hydrogen atom, or R6 together with R5 is an oxo group, R3 is a hydrogen atom, a lower alkyl radical or a hydroxyl group and R4 is a hydrogen atom, or salts thereof are antihyper- tensive and antiarrhythmic agents.

308039

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