Process for the preparation of optically active aminoalcohols

Details Process for the preparation of optically active aminoalcohols Process for the preparation of optically active aminoalcohols

C - Chemistry, Metallurgy

07

C

C07C 213/10 (2006.01) C07C 215/42 (2006.01) C07C 217/52 (2006.01) C07C 231/00 (2006.01) C07C 231/20 (2006.01) C07C 233/23 (2006.01) C07D 471/08 (2006.01) C12P 13/00 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2591818

A process is provided, for the preparation of (1S,4R)- or (1R,4S)-1-amino-4-(hydroxymethyl)-2- cyclopentene of formula V or VI, (see formula V and VI) or a salt thereof or of a(1S,4R)- or (1R,4S)-1-amino-4- (hydroxymethyl)-2-cyclopentene derivative of general formula VII or VIII, (see formula II) or a salt (VIII) thereof, wherein X and Y are identical or different and are an acyl group or H, with the exception of X = Y = H, comprising a racemate resolution of a racemic aminoalcohol of formula I, (see formula I) by biotechnological means using a hydrolase in the presence of an acylating agent.

Divulgation d'un procédé de préparation de (1S,4R)- ou (1R,4S)-1-amino-4- (hydroxyméthyl)cyclopent-2-ène de formule V ou VI (voir les formules V et VI), d'un sel de ces composés ou d'un dérivé de (1S,4R)- ou (1R,4S)-1-amino-4-(hydroxyméthyl)cyclopent-2-ène de formule générale VII ou VIII (voir la formule II) ou d'un sel (VIII) de ce dérivé, dans lesquels X et Y sont identiques ou différents et sont un groupement acyle ou un H, sauf lorsque X = Y = H. Ce procédé comprend la résolution par des moyens biotechnologiques d'un aminoalcool racémique de formule I (voir la formule I) faisant appel à une hydrolase en présence d'un agent d'acylation.

Affiliated with

Also associated with

Rating

Process for the preparation of optically active aminoalcohols does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of optically active aminoalcohols, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of optically active aminoalcohols will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1843665