Process for the preparation of optically pure or enriched...

Details Process for the preparation of optically pure or enriched... Process for the preparation of optically pure or enriched...

C - Chemistry, Metallurgy

07

C

C07C 45/78 (2006.01) C07C 45/79 (2006.01) C07C 49/697 (2006.01)

Patent

CA 2464916

A process for producing substantially optically pure sertraline utilizes chromatographic separation on a solid stationary chiral phase of spherical clay particles having an interlayer containing an optically pure metal-organic complex, and a liqiuid mobile phase preferably containing at least methyl acetate. The liquid mobile phase is preferably free of acetonitrile. The process is operable at temperatures above 40~C.

Dans un procédé de production de sertraline sensiblement optiquement pure, on utilise la séparation chromatographique sur une phase chirale fixe solide de particules sphériques d'argile comportant une couche intercalée contenant un complexe organométallique et une phase mobile liquide contenant de préférence au moins un acétate de méthyle. La phase mobile liquide est de préférence dépourvue d'acétonitrile. Ce procédé peut être mis en oeuvre à des températures supérieures à 40 ·C.

Affiliated with

Also associated with

Rating

Process for the preparation of optically pure or enriched... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of optically pure or enriched..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of optically pure or enriched... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1492717