C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/111, 260/118
C07D 499/00 (2006.01)
Patent
CA 1216842
A B S T R A C T Preparation of penicillanic acid 1,1-dioxide and derivatives thereof by debromination of 6-alpha-bromo- and/or 6,6-dibromo- penicillanic acid 1,1-dioxides. The debromination is effected in a water-containing medium by reduction with zinc in association with an acid having a pKa-value measured in water less than 3.5.
426046
Fasel Herman P.
Henniger Peter W.
Kapur Jagdish C.
Van Der Drift Johannes K.
Gist - Brocades N.v.
Osler Hoskin & Harcourt Llp
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