Process for the preparation of perindopril and salts thereof

Details Process for the preparation of perindopril and salts thereof Process for the preparation of perindopril and salts thereof

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2566754

The present invention relates to a process for the preparation of the ACE inhibitor (2S,3aS,7aS)-l-((2S)-2-(((1S)-l-(ethoxycarbonyl)butyl)amino)-l- oxopropyl)octahydro-lH-indol-2-carboxylic acid and of pharmaceutically acceptable salts thereof as well as to intermediates useful in said process.

L'invention concerne un procédé de préparation d'acide (2S,3aS,7aS)-l-((2S)-2-(((1S)-l-(éthoxycarbonyl)butyl)amino)-l-oxopropyl)octahydro-lH-indol-2-carboxylique inhibiteur de ACE et de sels acceptables sur le plan pharmaceutique de celui-ci, ainsi que des intermédiaires utiles dans ledit procédé.

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