C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/14 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) C07D 263/44 (2006.01) C07D 277/34 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 417/12 (2006.01) C12P 17/16 (2006.01)
Patent
CA 2123782
2123782 9310254 PCTABS00022 A process for preparing a compound of formula (I), or a tautomeric form thereof and/or a pharmaceutically acceptable salt thereof and/or a pharmaceutically acceptable solvate thereof, wherein: T represents a substituted or unsubstituted aryl group and T1 is O or S; which process comprises, treating a compound of formula (II), or a tautomeric form thereof and/or a salt thereof and/or a solvate thereof, wherein T and T1 are as defined in relation to formula (I), with a microbial reductase obtained from an appropriate red yeast; and thereafter, as required, preparing a pharmaceutically acceptable salt and/or a pharmaceutically acceptable solvate of the compound of formula (I) or a tautomeric form thereof: compounds prepared by such a process and the use of such compounds in medicine.
Hindley Richard M.
Woroniecki Stefan R.
Borden Ladner Gervais Llp
Smithkline Beecham P.l.c.
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