Process for the preparation of phenethylamine derivatives

Details Process for the preparation of phenethylamine derivatives Process for the preparation of phenethylamine derivatives

C - Chemistry, Metallurgy

07

C

C07C 213/02 (2006.01) C07C 217/74 (2006.01)

Patent

CA 2431065

Disclosed is a process for the preparation of a compoud of formula wherein R~1 is hydrogen, hydroxyl, or unsubstituted or substituted alkyl or alkoxy, R~2 is hydrogen or a substituent which can be converted to hydrogen, and n is 0, 1 or 2, comprising hydrogenating a compound of formula wherein R~1, R~2 and n are as defined above, in the presence of a nickel or cobalt catalyst.

L'invention concerne un procédé de préparation d'un composé correspondant à la formule (1) dans laquelle R1 représente hydrogène, hydroxyle, ou alkyle ou alcoxy substitué ou non, R2 représente hydrogène ou un substituant qui peut être converti en hydrogène, et n vaut 0, 1 ou 2. Ce procédé consiste à hydrogéner un composé correspondant à la formule (2) dans laquelle R1, R2 et n sont tels que définis ci-dessus, en présence d'un catalyseur à base de nickel ou de cobalt.

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