Process for the preparation of phtalide

Details Process for the preparation of phtalide Process for the preparation of phtalide

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) C07D 239/52 (2006.01)

Patent

CA 2268775

A process for preparation of substituted phthalides, heterocyclic phthalides and derivatives thereof of the formula I Image wherein A is phenyl or pyridyl; R is a carboxyl group; X and Y taken together represent = O; or X and R taken together may form a bridge, which process comprises reacting an aromatic carboxylic acid mono- or di-anion with a reactive derivative of a pyrimidine carboxylic acid.

L'invention concerne un procédé destiné à la préparation de phtalides substitués, de phtalides hétérocycliques et de leurs dérivés, par la mise en réaction d'un mono-anion ou d'un di-anion d'acide carboxylique aromatique avec un dérivé réactif d'un acide carboxylique de pyrimidine.

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