Process for the preparation of polycyclic compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 307/93 (2006.01) C07C 43/205 (2006.01) C07C 43/21 (2006.01) C07C 69/00 (2006.01) C07C 69/757 (2006.01) C07D 317/70 (2006.01) C07D 493/04 (2006.01) C07D 498/14 (2006.01)

Patent

CA 2067552

ABSTRACT Polycyclic compounds (I) can be prepared in ac- cordance with the following reaction formula: Image iron Image perchlorate ? TFA wherein R1-R8 each represents a hydrogen atom, a hydroxyl group, an alkoxyl group or a substituted or unsubstituted benzyloxy group or neighboring two groups of R1-R8 are coupled together to form an alkylenedioxy group; and A is an alkylene group which may be sub stituted by one or more alkoxycarbonyl groups, an alkenylene group which may be substituted by one or more alkoxycarbonyl groups, or a group represented by any one of the following formulas: Image , Image and Image . This facilitates the development of processes for the synthetic production of naturally occurring drugs.

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