Process for the preparation of polymers having nucleobases...

Details Process for the preparation of polymers having nucleobases... Process for the preparation of polymers having nucleobases...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C07C 291/10 (2006.01) C07D 239/54 (2006.01) C07D 405/12 (2006.01) C07D 473/34 (2006.01) C07K 5/06 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2290614

The invention relates to a method for producing polymers having nucleo-bases as side groups by means of multi-constituent reactions, specially the Ugi reaction. By virtue of the multiconstituent nature of production, the properties of the polymers can be varied to a greater degree than before and can be adapted to meet the requirements for use as antisense or antigen therapeutic agent or diagnostic reagent.

Dans la présente invention, on divulgue une méthode pour produire des polymères présentant des nucléobases comme groupes latéraux, au moyen de réactions avec plusieurs composants, en particulier au moyen d'une réaction de Ugi. Etant donné que cette production est fondée sur l'utilisation de plusieurs composants, on peut faire varier plus qu'avant les propriétés des polymères et les adapter afin de satisfaire aux exigences d'utilisation comme agent thérapeutique antisens ou antigénique ou comme réactif de diagnostic.

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