Process for the preparation of polymorphs of mesotrione

C - Chemistry – Metallurgy – 07 – C

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C07C 315/06 (2006.01) C07C 317/44 (2006.01)

Patent

CA 2575636

A process for selectively controlling the crystallisation of thermodynamically stable Form (1) or kinetically stable Form (2) polymorphs of mesotrione from an aqueous mesotrione solution, said method comprising adjusting the pH of the mesotrione solutions to a value wherein said thermodynamically stable Form (1) or kinetically stable Form (2) mesotrione is ultimately obtained is disclosed.

La présente invention concerne un procédé pour contrôler sélectivement la cristallisation de polymorphes de mésotrione thermodynamiquement stable de la Forme (1) ou cinétiquement stable de la Forme (2) à partir d'une solution aqueuse de mésotrione, ledit procédé comprenant le réglage du pH des solutions de mésotrione à une valeur à laquelle ladite mésotrione thermodynamiquement stable de Forme (1) ou cinétiquement stable de Forme (2) est finalement obtenue.

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