Process for the preparation of protease inhibitors

C - Chemistry – Metallurgy – 12 – N

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530/7.1, 195/1.2

C12N 15/00 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 14/815 (2006.01) C07K 16/38 (2006.01) C12N 5/00 (2006.01) C12N 9/99 (2006.01) C12P 21/00 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1297437

4-14660/1+2/+ Process for the preparation of protease inhibitors Abstract The invention relates to DNA sequences which code an eglin, expression plasmids containing such DNA sequences, hosts transformed with such expression plasmids, novel eglin compounds produced from such transformed hosts, monoclonal antibodies against eglins, hybridoma cells which produce such antibodies, and test kits for immunoassays containing such antibodies, and furthermore the processes for their prepara- tion and a process for the preparation of eglins with the aid of the transformed hosts. The eglins which can be prepared according to the invention have useful pharmacological pro- perties.

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