Process for the preparation of purified vancomycin class...

C - Chemistry – Metallurgy – 07 – K

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C07K 9/00 (2006.01) G01N 33/543 (2006.01) G01N 33/94 (2006.01)

Patent

CA 1238315

A PROCESS FOR THE PREPARATION OF PURIFIED VANCOMYCIN CLASS ANTIBIOTICS ABSTRACT A novel process for the isolation and purification of vancomycin class antibiotics which utilized affinity chromatography by the formation of a sorption complex between the antibiotic and an immobilizing ligand selected from -D-alanyl-D-alanine or -X-D-alanyl-D-alanine, wherein X is an amino acid radical and the novel affinity chromatography sorbent employed therein are disclosed.

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