Process for the preparation of pyrimidone derivatives with...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/06 (2006.01) A01N 43/653 (2006.01) A61K 31/517 (2006.01) C07D 239/90 (2006.01) C07D 249/08 (2006.01)

Patent

CA 2402390

Process for the preparation of pyrimidone derivatives of formula 1, which comprises reacting a compound of formula II with a compound of formula III in the presence of a base. The pyrimidone derivatives of formula I are useful as antifungal agents. (see formula I) (see formula II)(see formula III)

L'invention concerne un procédé de préparation de dérivés de pyrimidone représentés par la formule (I), lequel procédé est caractérisé en ce qu'il consiste à faire réagir un composé de formule (II) avec un composé de formule (III) en présence d'une base. Les dérivés de pyrimidone représentés par la formule (I) sont utiles comme agents antifongiques.

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