Process for the preparation of quinoline carboxylic acide

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

260/285, 260/266

C07D 401/10 (2006.01) C07D 215/56 (2006.01) C07F 5/02 (2006.01)

Patent

CA 1306750

A B S T R A C T The invention relates to a new process for the pre- paration of compounds of the general Formula I Image /I/ (wherein R stands for hydrogen or methyl) and pharma- ceutically acceptable salts thereof which comprises reacting a compound of the general formula V Image /V/ (wherein R1 and R2 stand for an aliphatic acyloxy group comprising 2-6 carbon atoms and optionally sub- stituted by halogen; or for an aromatic acyloxy group comprising 7-11 carbon atoms) with an amine of the general Formula VI Image /VI/ (wherein R has the same meaning as stated above) or a salt thereof and subjecting the compound of the general Formula VII /VII/ Image thus obtained (wherein R, R1 and R2 are as stated above) to hydrolysis after or without isolation and if desired converting the compound of the general Formula I thus obtained into a salt thereof or setting free the same from its salt. The compounds of the general Formula I are known antibacterial agents. The advantage of the process of the present inven- tion is that it makes the desired compounds of the ge- neral Formula I available in a simple manner, with high yields and in a short reaction time.

524724

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Process for the preparation of quinoline carboxylic acide does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of quinoline carboxylic acide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of quinoline carboxylic acide will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1303509

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.