Process for the preparation of racemic pilosinine derivatives

Details Process for the preparation of racemic pilosinine derivatives Process for the preparation of racemic pilosinine derivatives

C - Chemistry, Metallurgy

07

D

C07D 405/06 (2006.01) C07D 233/64 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2053791

Abstract The invention relates to a process for the preparation of racemic pilosinine derivatives as precursor for the alkaloid pilocarpine of pharmacological importance from a 5-formyl-1- imidazole of the formula I Image in which R1 is a low molecular weight straight-chain or branched alkyl chain with 1-6 C atoms which, via the stage of the thioacetal, is added onto .gamma.-crotonolactone. pat180791ei2

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