C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/367.1, 260/3
C07D 307/52 (2006.01) C07D 307/42 (2006.01)
Patent
CA 1263400
Abstract Ranitidine, which has the formula Image (I) is prepared by reaction of N-[2-[[[5-(hydroxymethyl)-2- furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethene- diamine, which has the formula Image (V) in an organic solvent, e.g. dimethylformamide, with dimethylamine and an N,N-(dimethylamino)-triphosphonium- halide having the formula Image wherein Hal denotes bromo or chloro.
518765
Alhede Borge
Clausen Finn Priess
A/s Gea Farmaceutisk Fabrik
Marks & Clerk
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