C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 503/02 (2006.01) A61K 31/42 (2006.01) C07D 503/00 (2006.01)
Patent
CA 2271847
An improved process for the preparation of pharmaceutically acceptable alkali metal salts or esters of clavulanic acid has been provided for. Furthermore, also potassium clavulanate with an extremely low amine content and pharmaceutical compositions comprising the same have been provided for.
L'invention porte sur un procédé amélioré de préparation de sels ou d'esters de métal alcalin pharmaceutiquement acceptables d'acide clavulanique. L'invention porte aussi sur un clavulanate de potassium ayant une teneur en amine extrêmement faible et sur des compositions pharmaceutiques le contenant.
Booij Johannes
Van Den Heuvel Antonius
Gist-Brocades B.v.
Osler Hoskin & Harcourt Llp
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