A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/245
A61K 9/20 (2006.01) A61K 31/34 (2006.01) A61K 31/345 (2006.01) A61K 47/00 (2006.01)
Patent
CA 1285489
ABSTRACT The present invention relates to obtaining isosorbide-5-mononitrate tablets, being also of retard form, which are stable in time. Such embodiment is now possible after the discovery of the stabilizing activity of the polyvinylpyrrolidone with respect to the isosorbide-5-mononitrate with which it forms a solid solution. The use of PVP is essential so that the tablets can remain stable in time: the retard effect in turn can be obtained with the use of hydroxyalkylcelluloses.
520377
Calanchi Massimo
Rossi Piergiorgio
Eurand International S.p.a.
Ridout & Maybee Llp
LandOfFree
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