A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01)
Patent
CA 2628176
The invention relates to a process for the preparation of pharmaceutical powders, the process comprising: a) solubilization of the pharmaceutical compound in water or in an organic solvent at a concentration close to saturation; b) evaporating the solvent at constant temperature while subjecting the solution to ultrasound. In another embodiment, the invention relates to a process for the preparation of sterile pharmaceutical compounds, the process comprising: a) solubilization of the pharmaceutical compound in water or in an organic solvent at a concentration close to saturation; b) sterilizing filtration of the solution by passing it through a hydrophobic filter (0,22 microns membrane); c) evaporating the solvent at constant temperature while subjecting the solution to ultrasound.
L'invention concerne un procédé destiné à préparer des poudres pharmaceutiques, le procédé consistant: a) à solubiliser le composé pharmaceutique dans de l'eau ou dans un solvant organique à une concentration proche de la saturation; b) à évaporer le solvant à une température constante tout en soumettant la solution aux ultrasons. Dans un autre mode de réalisation, l'invention concerne un procédé destiné à préparer des composés pharmaceutiques stériles, ce procédé consistant: a) à solubiliser le composé pharmaceutique dans de l'eau ou dans un solvant organique à une concentration proche de la saturation; b) à stériliser la filtration de la solution par passage de celle-ci à travers un filtre hydrophobe (membrane à 0,22 microns); c) à évaporer le solvant à une température constante tout en soumettant la solution aux ultrasons.
Oyen Wiggs Green & Mutala Llp
Pharmatex Italia Srl
LandOfFree
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