Process for the preparation of substituted...

Details Process for the preparation of substituted... Process for the preparation of substituted...

C - Chemistry, Metallurgy

07

D

C07D 473/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2080097

The preparation of N-(aryl)-1,2,4-triazolo- pyrimidine-2-sulfonamides by the coupling of substituted 1,2,4-triazolopyrimidine-2-sulfonyl halides with aryl amines of substantially reduced nueleophilie reactivity is facilitated by conducting the reaction in the presence of a pyridine base and a catalytic amount of dimethyl sulfoxide.

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