Process for the preparation of substituted pyrimidine...

Details Process for the preparation of substituted pyrimidine... Process for the preparation of substituted pyrimidine...

C - Chemistry, Metallurgy

07

D

C07D 239/40 (2006.01) C07D 239/36 (2006.01)

Patent

CA 2275400

The invention concerns a novel process for preparing substituted pyrimidine derivatives of general formula (I) in which a [3-(dimethylamino)-2-azaprop-2-en-1-ylidene]dimethylammonium halide is reacted with a substituted acetamide. The compounds of general formula (I) are important intermediate products for pharmaceutical or agrochemical active substances.

L'invention concerne un nouveau procédé de préparation de dérivés de pyrimidine substitués de la formule générale (I) dans laquelle un [3-(diméthylamino)-2-azaprop-2-ène-1-ylidène]halogénure de diméthylammonium est mis à réagir avec un acétamide substitué. Les composés de la formule générale (I) sont des produits intermédiaires significatifs pour des principes actifs pharmaceutiques ou agrochimiques.

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