A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/72 (2006.01) A61K 9/10 (2006.01) A61K 31/00 (2006.01)
Patent
CA 2581999
The present invention provides processes for preparing suspension aerosol formulations, wherein the particles for inhalation are formed in situ during the process of manufacturing the formulation. In one aspect of the invention, a process for preparing a suspension aerosol formulation comprises the steps of: (a) dissolving one or more medicaments in one or more solvents to form a solution; and (b) mixing one or more propellants with the solution under conditions effective to precipitate, entirely or partially, at least one of the medicaments.
La présente invention concerne des procédés de préparation de formulations d'aérosol en suspension. Selon ce procédé, les particules à inhaler sont formées in situ pendant le processus de fabrication de la formulation. Selon un aspect de cette invention, un procédé de préparation d'une formulation d'aérosol en suspension comprend les étapes consistant: (a) à dissoudre un ou plusieurs médicaments dans un ou plusieurs solvants pour former une solution; et (b) à mélanger un ou plusieurs propulseurs avec la solution dans des conditions permettant d'obtenir la précipitation totale ou partielle d'au moins un des médicaments.
Bovet Li Li
Holt Jay T.
Generics (uk) Limited
Osler Hoskin & Harcourt Llp
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