Process for the preparation of sustained release...

Details Process for the preparation of sustained release... Process for the preparation of sustained release...

A - Human Necessities

61

K

167/169

A61K 9/22 (2006.01)

Patent

CA 1225596

ABSTRACT A process for the preparation of sustained release tablets having an active ingredient content of at least 80% and possessing a structure which loosens in aqueous medium but does not disintegrate to discrete particles within 4 hours, in which the particles of the active ingredient are coated in a liquid medium with a water-insoluble polymer -preferably ethylcellulose- and then mixing the coated particles with at least one disinteg- rant which is capable swelling in aqueous medium, and then pressing the mixture into tablets.

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