Process for the preparation of tablets with retarded...

Details Process for the preparation of tablets with retarded... Process for the preparation of tablets with retarded...

A - Human Necessities

61

K

167/166

A61K 9/52 (2006.01) A61K 9/20 (2006.01)

Patent

CA 1144071

ABSTRACT A process for the preparation of matrix-type tablets with retarded liberation of the active agent. The liberation of the active agent from the tablets takes place at a speed that has been adjusted precisely in advance. In the granulation process, polymethacrylate plastics insoluble in neutral or slightly acid water either as dissolved in an organic solvent or as a water dispersion are used as the retarding matrix substance. Before the tablets are compressed, an ester of a large molecule fatty acid or a product obtained from same by means of hydrogenation is mixed into the grain mix in order to adjust the rate of liberation of the active agent.

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