Process for the preparation of taurine-conjugated bile acids

Details Process for the preparation of taurine-conjugated bile acids Process for the preparation of taurine-conjugated bile acids

C - Chemistry, Metallurgy

07

J

C07J 41/00 (2006.01) C07J 9/00 (2006.01)

Patent

CA 2101381

Abstract Process for the preparation of taurine-conjugated biliary acids of general formula (I): (Y-NH-CH2-CH2-SO3)1M (I) where Y is the acyl of a biliary acid selected from the group consisting of ursodeoxycholic, chenodeoxycholic, lithocholic, 3.alpha.-7.beta.- 12.alpha.-tri-hydroxycholanic, 3.alpha.-7.beta.-dihydroxy-12-ketocholanic, deoxycholic, dehydrocholic, iodeoxycholic, iocholic acids; M is H, Na, K, Mg, Ca; 1 is 1 or 2, being 2 when M = Mg or Ca.

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