Process for the preparation of the amorphous form of...

Details Process for the preparation of the amorphous form of... Process for the preparation of the amorphous form of...

C - Chemistry, Metallurgy

07

D

C07D 207/34 (2006.01)

Patent

CA 2483862

Process for preparing atorvastatin calcium salt in amorphous form comprising: a) dissolving the atorvastatin calcium salt in an organic solvent miscible with water, b) gradually adding said solution to water while stirring, c) filtering and vacuum drying the solid obtained. Formula.

L'invention concerne un procédé de préparation d'un sel d'atorvastatine calcique amorphe consistant: a) à dissoudre le sel d'atorvastatine calcique dans un solvant organique miscible avec de l'eau, b) à ajouter graduellement cette solution à l'eau tout en brassant, c) à filtrer et à sécher sous vide le solide obtenu.

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