Process for the preparation of the mesylate salt trihydrate...

Details Process for the preparation of the mesylate salt trihydrate... Process for the preparation of the mesylate salt trihydrate...

C - Chemistry, Metallurgy

07

D

C07D 211/52 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2345286

The present invention is directed to a novel process for the preparation of the mesylate trihydrate of the compound of formula (I), (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol: (see formula I) The present invention is further directed to a process for the preparation of a (2S)-(+)- compound of formula (II): (see formula II) wherein R1 is a protecting group. In addition, the present invention relates to intermediates useful in said processes.

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