Process for the preparation of thiadiazole derivatives...

Details Process for the preparation of thiadiazole derivatives... Process for the preparation of thiadiazole derivatives...

C - Chemistry, Metallurgy

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D

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C07D 413/12 (2006.01) A61K 31/535 (2006.01) C07D 285/12 (2006.01) C07D 285/135 (2006.01)

Patent

CA 1259990

PROCESS OR THE PREPARATION OF THIADIAZOLE DERIVATIVES ACTIVE ON THE CENTRAL NERVOUS SYSTEM ABSTRACT OF THE DISCLOSURE The invention relates to thiadiazole derivatives corresponding to the formula: Image in which R represents: - a linear or branched alkyl group having from 1 to 5 carbon atoms; - a cycloalkyl group having 5 or 6 carbon atoms; - a phenyl group optionally substituted by 1 or 2 halogen atoms, preferably chlorine, by 1 or 2 lower alkyl or lower alkoxy groups, by 1 or 2 hydroxyl groups or by a nitro or trifluoromethyl group; - a biphenylyl group; or - an alpha-naphthyl group; and pharmaceutically acceptable salts of the said derivatives. The said derivatives possess valuable therapeutic properties on the central nervous system.

492711

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