Process for the preparation of thieno [2,3-c] and [3,2-c]...

Details Process for the preparation of thieno [2,3-c] and [3,2-c]... Process for the preparation of thieno [2,3-c] and [3,2-c]...

C - Chemistry, Metallurgy

07

D

260/276.1

C07D 495/04 (2006.01)

Patent

CA 1106377

ABSTRACT OF THE DISCLOSURE This invention relates to a process for the prepa- ration of a compound selected from the compounds having the formulae: Image Image and (I) (II) in which: R1 represents hydrogen, a halogen atom or a lower alkyl radical, a lower alkoxy radical or a lower alkylthio radical; R2 represents hydrogen or a lower alkyl, aralkyl, aryl, carboxy or alkoxycarbonyl radical or an aryloxy carbonyl radical; R3 represents hydrogen, a C1-12 alkyl radical, or an aralkyl or aryl radical, optionally substituted on the aromatic nucleus with one or more halogen atoms or hydroxy, nitro, cyano, carboxamido, carboxy, alkoxycarbonyl, lower alkyl, lower alkoxy or trifluoromethyl groups; and n is zero or 1. Said new compounds possess therapeutically useful blood-platelet aggregation inhibiting properties and also anti-thrombotic, anti-sludge, antalgic and anti-inflammatory properties.

299760

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