Process for the preparation of thymol

C - Chemistry – Metallurgy – 07 – C

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260/622.1

C07C 39/06 (2006.01) C07C 37/14 (2006.01)

Patent

CA 1077522

Abstract of the Disclosure A continuous process for the preparation of thymol by propylation of m-cresol with propylene and/or compounds which eliminate propylene, char- acterized in that the reaction is carried out over aluminium oxide catalysts in the presence of a nitrogen base. This process is distinguished by the fact that it yields, even in the presence of small amounts of water in the m- cresol, and independently of the starting material, that is to say independent- ly of whether m-cresol and propylene, or by-products arising in working up crude thymol, are employed, a crude thymol of constant composition and quality from which thymol in a purity of over 99.5% can be isolated without dif- ficulties, and the by-products of which can always be recycled to the reaction. In the process according to the invention, the activity of the catalyst also remains preserved for very long periods.

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