Process for the production of 2-(methylthio)-disodium...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/66 (2006.01) C07D 239/68 (2006.01)

Patent

CA 2076690

A process is disclosed for the production of 2- (methylthio)-disodium barbiturate by reacting thiourea, malonic acid dimethyl ester and sodium methanolate to form disodium thiobarbiturate. The disodium thiobarbiturate is then reacted with methyl bromide, optionally in the presence of a base, to form the desired end product.

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