C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/315.25
C07D 233/60 (2006.01) C07D 521/00 (2006.01)
Patent
CA 1173839
ABSTRACT OF THE DISCLOSURE 4-(1-Imidazolylmethyl)cinnamic acid hydrochloride monohydrate of the formula: Image The imidazole derivative above has a strong and specific inhibitory effect on thromboxane synthetase from human or bovine platelet microsomes, and is useful as a therapeutical agent for inflammation, hypertension, thrombus, cerebral apoplexy, and asthma.
395781
Akahane Kenji
Arikawa Shigeo
Iizuka Kinji
Morita Kaname
Watanabe Mitsuo
Kissei Pharmaceutical Co. Ltd.
Ono Pharmaceutical Co. Ltd.
Riches Mckenzie & Herbert Llp
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