Process for the production of 4-amino-6,7-dimethoxy-2-...

Details Process for the production of 4-amino-6,7-dimethoxy-2-... Process for the production of 4-amino-6,7-dimethoxy-2-...

C - Chemistry, Metallurgy

07

D

260/253, 260/466

C07D 405/14 (2006.01) C07D 239/95 (2006.01) C07D 405/12 (2006.01)

Patent

CA 1243677

A B S T R A C T The invention relates to a new multistage process for the production of 4-amino-6,7-dimethoxy-2-[4-(furo- 2-yl)-piperazin-1-yl]-quinazoline corresponding to the following formula Image and physiologically compatible salts thereof, which gives better yields and uses less expensive and more reactive materials than known processes. The intermediate product formed in this process, N''-cyano- N'-(3,4-dimethoxyphenyl)-0-phenylisourea, shows antihypertensive activity on its own. 3838

448121

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