Process for the production of 4 - hydroxy -6-...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/34 (2006.01) C07D 239/36 (2006.01) C07D 239/42 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2014533

ABSTRACT OF THE DISCLOSURE A process is disclosed for the production of 4- hydroxy-6-polyfluoroalkylpyrimidines, starting from a polyfluoroalkylcarbonylacetic acid lower alkyl ester and a formamidine salt. 4-Hydroxy-6-pentafluoroethylpyrimidine is an intermediate product. The 4-hydroxy-6- polyfluoroalkylpyrimidines can be used for the production of trifluoromethylpyrimidines, trifluoromethylpurines and pentafluoroethylpyrimidines.

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