C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 33/02 (2006.01)
Patent
CA 2070391
A process for the production of 4-pregnene-3,20-dione and its derivatives of general formula I Image in which R1 means a hydrogen atom, a fluorine atom or a methyl group, R2 represents a hydrogen atom or a hydroxy group, and R3 and R4 together symbolize a carbon-carbon bond or R3 represents a hydrogen atom, a hydroxy group or an alkanoyloxy group with up to 6 carbon atoms and R4 means a hydrogen atom or a methyl group, is described, which is characterized in that a pregnane derivative of general formula II Image in which R1, R3 and R4 have the above-mentioned meaning, ~ symbolizes a single bond or a double bond, R5 represents a hydrogen atom, a hydroxy group or an alkanoyloxy group with at most 6 carbon atoms and R6 means a hydrogen atom or an alkanoyl group with at most 6 carbon atoms, is fermented with a bacterial culture of species Mycobacterium spec. NRRL B-3805.
Kennecke Mario
Weber Alfred
Marks & Clerk
Schering Aktiengesellschaft Berlin Und Bergkamen
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