Process for the production of 7-adca via expandase activity...

Details Process for the production of 7-adca via expandase activity... Process for the production of 7-adca via expandase activity...

C - Chemistry, Metallurgy

12

P

C12P 35/00 (2006.01) C12N 9/02 (2006.01) C12N 15/52 (2006.01)

Patent

CA 2223105

An overall process for the preparation and recovery of 7- aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G, using a Penicillium chrysogenum transformant strain expressing expandase.

L'invention concerne un procédé global de préparation et de récupération de l'acide 7-aminodesacetoxycephalosporanique (7-ADCA) par expansion enzymatique du cycle de la pénicilline G en utilisant une souche transformée de Penicillium chrysogenum capable d'exprimer une expandase.

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