C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
260/229.5
C07H 19/20 (2006.01)
Patent
CA 1077030
Abstract of the Disclosure: Process for the production of an ester product, 9-(.beta.-D-arabinofuranosyl)adenine, 5'-phosphate, in which the mixture resulting from reaction of 9-(.beta.-D-arabino- furanosyl)adenine with phosphorylating agent in tri- alkyl phosphate solvent is subjected to aqueous hydrolysis, the pH of the hydrolysis mixture is adjusted upward sufficiently to cause separation into aqueous and non-aqueous liquid phases, the trialkyl phosphate solvent is removed, and the product is precipitated from the residual aqueous mixture and isolated.
290047
Behnke Walter E.
Haskell Theodore H.
Marsh William R.
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