Process for the production of a dicarboxylic acid

Details Process for the production of a dicarboxylic acid Process for the production of a dicarboxylic acid

C - Chemistry, Metallurgy

12

P

C12P 7/46 (2006.01)

Patent

CA 2714088

The present invention relates to a process for the production of a dicarboxylic acid wherein a eukaryotic cell is fermented in a suitable fermentation medium. The invention further relates to a eukaryotic cell comprising a nucleotide sequence encoding an enzyme which catalyses the conversion of isocitric acid to succinic acid, and a nucleotide sequence encoding an enzyme which catalyses the conversion of glyoxylic acid to malic acid.

La présente invention porte sur un procédé de production d'un acide dicarboxylique, suivant lequel une cellule eucaryote est fermentée dans un milieu de fermentation approprié. L'invention porte en outre sur une cellule eucaryote comprenant une séquence nucléotidique codant pour une enzyme qui catalyse la conversion d'acide isocitrique en acide succinique, et une séquence nucléotidique codant pour une enzyme qui catalyse la conversion d'acide glyoxylique en acide malique.

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