Process for the production of a nanoemulsion of oil...

Details Process for the production of a nanoemulsion of oil... Process for the production of a nanoemulsion of oil...

C - Chemistry, Metallurgy

12

N

195/40, 134/52

C12N 1/38 (2006.01) A61K 9/107 (2006.01) C12N 1/00 (2006.01)

Patent

CA 2019710

Abstract of the Disclosure An aqueous phase, an oil of a triglyceride or fatty acid ester, and, per part by weight of oil, 0.05 to 0.4 part by weight of an amphoteric emulsifier are mixed together and processed in a high-pressure homogenizer into a nanoemulsion of less than 200 nm sized oil particles. The emulsifier, exhibiting in the aqueous phase a lamellar liquid-crystalline structure, is preferably a glycero- phosphatide of the formula Image Therein, R1 and R2 mean acyloxy and/or alkyl or alkenyl ether. R3 is a tri-lower-alkyl ammonio or amino- substituted lower alkyl. The resultant nanoemulsion is stable for a period of several months and does not contain any toxic emulsifier materials. Therefore, it can be advantageously utilized as a vehicle for active agents, for example medicines and/or cosmetic ingredients.

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