C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/072 (2006.01) C07K 1/08 (2006.01) C07K 5/068 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2260450
Process for the production of alkoxycarbonyldipeptides intermediates in the synthesis of the lisinopril which comprises protecting both amino functions of the L- lysine with an alkoxycarbonyl group, subsequently making the N-carboxyanhydride of the N6-[alkoxycarbonyl]-L-lysine by treatment with thionyl chloride and making the desired alkoxycarbonyldipeptide by reaction with L-proline in alkaline medium.
Cannata Vincenzo
Merli Valeriano
Saguatti Stefano
Marks & Clerk
P.f.c. Italiana S.r.l.
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