Process for the production of an influenza vaccine

Details Process for the production of an influenza vaccine Process for the production of an influenza vaccine

C - Chemistry, Metallurgy

12

N

C12N 5/071 (2010.01) A61K 39/145 (2006.01) C12N 7/02 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2566858

The present invention relates to a commercial-scale process for the production of influenza virus or antigens for prophylactic, diagnostic, immunotherapeutic or therapeutic purposes. Particularly, the invention provides a Madin-Darby Canine Kidney (MDCK)-derived, cell line and a cell culture-based process for the production of an influenza vaccine and more particularly, a human vaccine comprising influenza types A and B.

La présente invention concerne un procédé à l~échelle commerciale pour la production de virus de la grippe ou d~antigènes à des fins de prophylaxie, de diagnostic, d~immunothérapie ou de thérapie. Particulièrement, l~invention fournit un procédé basé sur la lignée cellulaire et la culture cellulaire dérivées de cellules canines de rein Madin-Darby (MDCK) pour la production d~un vaccin contre la grippe et plus particulièrement, d~un vaccin humain englobant les grippes de types A et B.

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