Process for the production of basic substituted alkyl...

C - Chemistry – Metallurgy – 07 – D

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260/242.4

C07D 473/08 (2006.01)

Patent

CA 1083571

ABSTRACT OF THE DISCLOSURE Basic substituted alkyl theophylline derivatives of the formula Image (I) are produced by catalytic hydrogenation of compounds of the formula Image (II) where the phenolic hydroxyl groups and/or the secondary basic nitrogen atom can contain protective groups using as the solvent a compound of the formula Image (III) where R', R" and R"' are the same or different and are alkyl groups of 1 to 2 carbon atoms and R' together with R''' can also be an alkylene bridge with 3 to 4 carbon atoms and in a given case the protective groups present are split off.

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