Process for the production of ergoline derivatives

Details Process for the production of ergoline derivatives Process for the production of ergoline derivatives

C - Chemistry, Metallurgy

07

D

260/206

C07D 457/00 (2006.01) C07D 457/04 (2006.01) C07D 457/12 (2006.01)

Patent

CA 1291120

Abstract of the Disclosure Ergoline derivatives of general Formula I Image wherein C8 Image C9 and C9 Image C10 are both CC-single bonds or one is a C=C-double bond, R6 is C1-4 alkyl, R8 is methyl, hydroxymethyl, carbonylmethoxy, ureido or N,N-diethylureido, each in the .alpha.- or .beta.-posi- tion, and R is hydrogen or nitro, are prepared by dehydrogenation of corresponding 2,3-dihydroergoline derivatives using an electrophilic reagent in an apolar solvent and a base.

497512

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